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RO5263397 can be a TAAR1 unique agonist with oral action that has been Employed in antidepressant reports. It has also been found to work as an inhibitor in the enzyme cyclooxygenase-two (COX-2), which is involved with the synthesis of prostaglandins.a, Illustration from the simulation setup used to evaluate binding of negatively charged DNP on the
DailyMed will provide notification of updates and additions to Drug Label details at this time revealed on This page through its RSS feed.The concurrent use of the drug with strong diuretics for instance ethacrynic acid or furosemide need to be averted, given that selected diuretics by themselves may well lead to ototoxicity.＊Acknowledge as Remed